Case Presentation: A 24-year-old Caucasian female with a family history of multiple autoimmune disorders presented with 3 weeks of bruising, petechiae, fatigue, and outside labs that revealed significant anemia and thrombocytopenia. Admission workup showed Hgb 7.6, platelets (PLT) < 3,000, and elevated MCV. Further labs showed elevated LDH, indirect bilirubinemia, haptoglobin< 10, and positive DAT [...]

Case Presentation: A 63-year-old male was admitted to the hospital for dizziness secondary to heart failure exacerbation and incidentally found to have thrombocytopenia of 141,000 on admission. Over the next 72 hours, the patient’s platelet count decreased by over 50% to 51,000 while all other cell lines remained stable. The patient had not received any [...]

Case Presentation: A 48-year-old male with past medical history significant for hypertension, alcohol use disorder in remission, known grade I esophageal varices, and cirrhosis who presented with confusion and oral mucosa bleeding. He was tachycardic to 100 but had adequate blood pressure of 106/68. Initial labs remarkable for hemoglobin 9.4 g/dL and platelet count 1 [...]

Case Presentation: A 65-year-old woman with antiphospholipid syndrome (APLS), and history of multiple lower extremity deep vein thrombosis (DVT) and miscarriages, on warfarin presented with syncope, fall, and head-strike. She was found to have an acute subdural hematoma (SDH) in the interhemispheric fissure and a non-occlusive DVT in the left femoral vein. Initial labs showed [...]

Case Presentation: A 66 year old female with a past medical history of hypertension (HTN), hyperlipidemia (HLD) and coronary artery disease (CAD) presented to the hospital for an elective three-vessel coronary artery bypass graft involving the left internal mammary artery to left anterior descending artery, saphenous vein graft (SVG) to the obtuse marginal artery, and [...]

Case Presentation: A 29-year-old female Jehovah’s Witness presented with three weeks of easy bruising in the absence of trauma. She also noticed heavier and prolonged menstrual flow associated with fatigue and dizziness. She denied medication use, febrile illnesses or neurologic symptoms. Vital signs were normal. Physical exam revealed multiple ecchymoses on bilateral upper and lower [...]