Background: Clinical handbooks support patient care, with studies demonstrating positive effects in areas such as quality of chart documentation, clinical knowledge, and value of inpatient care. Internal medicine residents rotating through inpatient services are particularly likely to benefit from handbooks, especially when handbooks share local, system-specific, and practical guidance. However, less is known about how [...]

Case Presentation: A 24-year-old Caucasian female with a family history of multiple autoimmune disorders presented with 3 weeks of bruising, petechiae, fatigue, and outside labs that revealed significant anemia and thrombocytopenia. Admission workup showed Hgb 7.6, platelets (PLT) < 3,000, and elevated MCV. Further labs showed elevated LDH, indirect bilirubinemia, haptoglobin< 10, and positive DAT [...]

Case Presentation: A 69-year-old male with hypertension, prostate cancer in remission, and recent diagnosis of lymphoma presented after experiencing a fall. Prior workup for abdominal pain, fever, night sweats, and weight loss revealed splenomegaly, anemia, and diffuse lymphadenopathy. Bone marrow biopsy demonstrated malignant lymphoma with prominent follicular helper T-cell component occupying 25-30% of the sampled [...]

Case Presentation: A 36-year-old male with no past medical history presented to the emergency room for medical evaluation for one week of diarrhea that became bloody four days prior to presentation. During the hospitalization, he had worsening thrombocytopenia and labs were consistent with Shiga Toxin 2 positive hemolytic uremic syndrome. He was managed with supportive [...]

Case Presentation: A 22-year-old Filipino man presented with worsening left groin and hip pain 2 weeks after falling down 3 steps on subway stairs. Since the fall, he had minimal range of motion due to pain and required assistance with ambulation. He also reported intermittent dull achiness in that hip one week prior to the [...]

Case Presentation: The patient is a 43-year-old female with asthma, hypertension, and obesity who presented to her PCP for cough, pharyngitis, and dyspnea. Exam revealed jaundice, livedo reticularis, and pallor. Complete blood counts (CBC) showed white blood cells 22.8 x109/ L, hemoglobin 8.9 g/dL, and platelets 674 ×109/L. Her family history had no hematologic malignancies [...]

Case Presentation: A 37-year-old previously healthy woman developed nausea, non-bloody vomiting and abdominal cramping a few hours after eating a beef chili followed by two episodes of self-limiting “chocolate” colored diarrhea. She presented three days later with persistent nausea, increasing fatigue and lethargy. Vital signs included a heart rate of 99/minute, blood pressure of 117/74 [...]

Case Presentation: We present the case of an 18-year-old female with no medical history presented to the emergency department with a two-day history of jaundice and dark-colored urine. She had no other typical symptoms of IM like sore throat, fever or flu-like symptoms. The only medication that she has been taking regularly is oral contraceptive [...]