Background: Revefenacin (REV), a once-daily, long-acting muscarinic antagonist for nebulized inhalation, was recently approved for maintenance treatment of chronic obstructive pulmonary disease (COPD). We present post hoc efficacy and safety data from three phase 3 trials in patients with moderate to very severe COPD by patient subgroup (<65 y, 65–75 y, >75 y). Methods: This [...]

Background: Neonatal abstinence syndrome (NAS) occurs when an infant is exposed to licit or illicit chemical substances in utero and manifests symptoms of withdrawal from the substance(s) after birth. NAS is a clinical diagnosis, but is generally confirmed with testing of infant urine and/or meconium to identify specific causative substances. Appropriate identification, documentation, and communication [...]

Case Presentation: A 14yo girl presented with syncope and 4 days of URI symptoms. She had no past medical or family history. On presentation, she was hypotensive with mildly elevated lactate, troponin, and BNP, and an unremarkable ECG and chest radiograph. Initial echocardiogram showed normal LV function. Cardiac MRI revealed a pericardial effusion and increased [...]

Case Presentation: A previously healthy 21-year-old man presented to the emergency department with a three-day history of rash, fever, and fatigue. The rash first appeared on his trunk and spread to his arms and hands on the first day of illness. Over the next two days, he developed worsening fevers and fatigue, and was sleeping [...]

Case Presentation: A 43-year-old male with roux-en-y gastric bypass fourteen years ago with complications and multiple adhesions, hiatal hernia associated with nausea and vomiting, and subsequent small bowel resection last year, started to experience cognitive changes and short-term memory loss. He has also experienced problems with balance, generalized weakness, and unintentional 60-pound weight loss. His [...]

Case Presentation: A 71-year-old woman with poorly differentiated squamous cell carcinoma (SCCA) of the left cheek with recent initiation of nivolumab therapy presented to the Emergency Department with five days of bilateral thigh pain, generalized weakness, and dyspnea. The exam was remarkable for tachycardia, hypotension, tachypnea as well as neck and proximal muscle strength weakness. [...]

Case Presentation: Our patient is a 58 year-old Portuguese-speaking female with a history of CLL and autoimmune hemolytic anemia who presented with severe epigastric pain, nausea, and vomiting. She presented with similar symptoms requiring two prior admissions within the last 6 weeks. CT scan of the abdomen and pelvis showed bowel wall thickening and hyperenhancement [...]

Case Presentation: The patient is a 35-year-old female who presented to the emergency department with a chief complaint of abdominal swelling and 10-pound weight gain over the last month. She also reported diffuse abdominal pain, nausea, and vomiting during this time. She had a past medical history of fibromyalgia. She had no relevant social or [...]

Case Presentation: A 57-year-old woman with type 1 diabetes on insulin pump and hypertension presented to the ED with abdominal pain with associated nausea/vomiting and shortness of breath for one day. She reported her insulin pump has been malfunctioning for several days. She denied fever/chills, chest pain, or diarrhea. She denied any toxic habits.Vital signs [...]

Case Presentation: A 70-year-old man was admitted to our hospital due to prolonged fever and progressive polyarthritis. He had progressive supranuclear palsy and needed a cane when walking. Six-months before admission for his current illness, he had high fever and arthralgia in the right elbow, which was treated with loxoprofen. However, loxoprofen produced only temporary [...]