Case Presentation: A 53-year-old man with a history of insulin-dependent type 2 diabetes mellitus presented with the complaint of abdominal pain, emesis and poor oral intake for three days. CT scan revealed non-obstructing nephrolithiasis. He was started on continuous IV fluids and pain management. Initial urinalysis revealed glucosuria >1000 mg/dL and negative ketones. Home medications [...]

Case Presentation: A 70-year-old woman visiting from India with history of hypothyroidism and adrenal insufficiency presented with four days of profuse diarrhea and fever. She was admitted for sepsis secondary to Rotavirus gastroenteritis with initial sodium level 132 (135-145 mmol/L). On day 2 of hospitalization, sepsis resolved with isotonic fluids and stress dose steroids, but [...]

Background: Hyperkalemia occurs frequently in diabetes. Sodium zirconium cyclosilicate (SZC), an oral, selective potassium (K) binder, rapidly reduces K in patients (pts) with hyperkalemia and has been shown to maintain normokalemia for up to 1 y. We compared the response to SZC in adults with and without diabetes mellitus (DM, type 1/2) in a 12 [...]

Background: The role of aspirin in primary prevention of cardiovascular events remains controversial, Especially in diabetic patients. We have conducted a meta-analysis of all randomized controlled trials (RCTs) to evaluate the efficacy and safety of aspirin for primary prevention in diabetic patients. Methods: Literature search of Pubmed, MEDLINE, Cochrane Library and Clinicaltrials.gov for related RCTs [...]

Background: Hyperglycemia and hyperosmolarity are frequent causes of hospitalization in patients with type II Diabetes Mellitus (T2DM). As a result, these conditions are associated with increased mortality, morbidity and increased health costs. This study examines the outcomes of patients with T2DM admitted for hyperglycemia and hyperosmolarity. Methods: Vizient database is a large administrative database and [...]

Background: Several studies have examined the impact of hypoglycemia in diabetic patients. These studies usually have reported relatively worse outcomes with hypoglycemia in diabetics. However, differences in outcomes in type I and II diabetes mellitus (DM) patients with hypoglycemia have not been well examined. Methods: The objective of this study was to examine differences in [...]

Background: Diabetes affects 30.3 million people in the US, and 25% of total hospital days are incurred by patients with diabetes. Among hospitalized adults, diabetes is considered a chronic secondary diagnosis. As the population of patients with diabetes grows, so does the potential for adverse events during hospitalization. Previous studies have shown that both hyper- [...]

Background: The use of intraoperative dexamethasone has been on the rise because of its ability to reduce postoperative nausea, vomiting, pain and accelerate post-operative recovery. Use of intraoperative dexamethasone can result in uncontrolled hyperglycemia in the postoperative period especially in patients with a diagnosis of diabetes. The extent and duration of post-operative steroid-induced hyperglycemia is [...]

Background: Hyperglycemia in hospitalized patients is well-known to be associated with adverse outcomes, such as infectious complications, increased length of stay, and increased mortality. To that effect, aggressive treatment of inpatient hyperglycemia has been shown to improve outcomes in both Medicine units and MICU. This study aimed to identify the number of patients experiencing persistent [...]

Background: Glucose management of hospitalized patients with hyperglycemia has many challenges. One of these challenges is the timing of insulin administration in coordination with meal delivery. The Endocrine Society recommends assessing glucose levels within 60 minutes of prandial insulin administration and that rapid-acting insulin should be administered 15 minutes before or immediately after a meal.1 [...]