Background: Prior exposure to antibiotics is associated with a subsequent risk for sepsis (Baggs et al., 2018). However, there are limited data on characteristics of patients readmitted with sepsis following previous antibiotic exposure during a non-sepsis related hospitalization. We sought to characterize factors associated with sepsis-related readmission (SRR) within 30 days of a non-sepsis index [...]

Background: Transjugular intrahepatic portosystemic shunt (TIPS) creation is a commonly utilized procedure used for patients with chronic liver disease and resistant portal hypertension. Previous studies have explored the trends and short-term outcomes in TIPS procedures. This study aims to further compare short-term in-hospital outcomes of patients with chronic kidney disease when undergoing TIPS. Methods: This [...]

Background: Transjugular intrahepatic portosystemic shunt (TIPS) creation is a commonly utilized procedure used for patients with chronic liver disease and resistant portal hypertension. Previous studies have explored the trends and short-term outcomes in TIPS procedures. This study aims to further compare short-term in-hospital outcomes of patients with coagulation disorders when undergoing TIPS. Methods: This retrospective [...]

Background: Transjugular intrahepatic portosystemic shunt (TIPS) creation is a commonly utilized procedure used for patients with chronic liver disease and resistant portal hypertension. Previous studies have explored the trends and short-term outcomes in TIPS procedures. This study aims to further compare short-term in-hospital outcomes of patients with diabetes mellitus (DM) when undergoing TIPS. Methods: This [...]

Background: Sepsis is associated with a six-fold greater risk of developing new-onset atrial fibrillation (AF). Patients with new onset AF demonstrate increased risk of stroke, vascular events, and death. However, the characteristics and management of new onset AF have not been well-described. Methods: We conducted a retrospective cohort study of patients aged ≥ 18 years [...]

Background: The approach to managing and admitting patients with syncope in an emergency setting lacks standardization. Our study aims to investigate how regional variation in management of emergency department (ED) patients presenting with syncope impacts outcomes and resource utilization in this patient population. Methods: We used the 2006 to 2014 Nationwide Emergency Department Sample to [...]

Background: ST-segment elevation myocardial infarctions (STEMI) is a significant cause of morbidity and mortality in the United States. Inter-hospital transfers (IHT) are becoming the standard for treatment of ST-elevation myocardial infarctions (STEMIs) as specialized care is often concentrated at tertiary centers. The American Heart Association and the American College of Cardiology (AHA/ACC) recommends door-to-balloon time [...]

Background: Factor concentrates such as 4 factor-prothrombin complex concentrate (4F-PCC) are commonly used off-label as reversal agents in factor Xa inhibitor-associated bleeding events. However, there have been limited studies on the efficacy and safety of 4F-PCC use in these settings. We conducted a retrospective observational study of the use of 4F-PCC for major bleeding occurring [...]

Background: Gamification and social incentives, such as family/peer engagement in goal-setting and feedback, are increasingly used by employers and health plans to promote physical activity and lose weight in outpatient settings but these approaches have not been used to improve mobility and reduce hospital-associated functional decline after hospital discharge. Methods: 12-week randomized, controlled trial of [...]

Background: Acute pancreatitis (AP) is one of the most common causes of hospitalization in the United States. Intravenous hydration with normal saline (NS) is the most commonly used fluid for resuscitation. Recent studies have shown better outcomes with the use of more pH balanced fluid-like ringer’s lactate and Plasmalyte (PL). We conducted a retrospective cohort [...]