Background: Individuals with autoantibodies against melanoma differentiation-associated protein 5 (MDA-5) are reported to have a significant risk of developing rapidly progressive and fatal interstitial lung disease (ILD) in clinically amyopathic dermatomyositis patients (CADM). Previous cohort studies of dermatomyositis patients who have been systematically evaluated for the presence of anti-MDA5 antibodies and associated clinical features and [...]

Case Presentation: A 56-year-old African American male with hyperlipidemia on a statin presented with two days of generalized abdominal pain, malaise, and weakness. Physical exam was unremarkable. Initial labs were notable for WBCs of 22.7 X103/ml, creatinine phosphokinase (CPK) of 28,992 U/L, BUN/Cr of 82/2.02, and AST of 957 U/L. Urine dipstick was positive for [...]

Case Presentation: A 68-year-old man with hypertension and osteoarthritis presented with fever, cough, dyspnea, and weight loss for 2 months. Prior to admission, he had received antibiotics for community-acquired pneumonia without improvement. Physical exam showed multiple ulcers at the base and sides of tongue, bilateral palmar erythematous papules with ulceration and scaling, bilateral erythematous plaques [...]

Case Presentation: A 24-year-old man with a history of relapsing juvenile dermatomyositis inactive for five years presented with one week of anosmia, dysgeusia, and rash. He also had fatigue and myalgias but no fevers, cough, or dyspnea. His exam was notable for a diffuse maculopapular rash with occasional crusted papules on the proximal upper and [...]

Case Presentation: A 35-year-old Caucasian male patient presented to our clinic complaining of fatigue, proximal muscle weakness, and pain. Twelve years ago, he was diagnosed with acute myeloid leukaemia, and due to poor prognostic factors, he underwent allogeneic HSCT from his sister, an HLA full-matched sibling donor. His past medical history is significant for chronic [...]

Case Presentation: 64-year-old female with a past medical history of cerebral palsy presented with recurrent fever. One week earlier, she had been hospitalized for sialadenitis and pneumonia and completed a 10 day course of antibiotics. Family reported recurrent fevers (Tm 102F) after discharge with associated mucosal ulcerations and chronic intermittent joint pain. She did not [...]

Case Presentation: An 81-year-old female with history of hypertension and hip osteoarthritis presented from rehabilitation facility with worsening right hip pain, back pain and lower abdominal pain. Laboratory work-up at the facility revealed several derangements, including elevated leukocytes. Patient was afebrile with tachycardia of 106. Pertinent examination findings included tender flexion at the right hip [...]