Case Presentation: A 22-year-old woman with a history of Adult Onset Still’s Disease presented with one week of acute abdominal pain, dyspnea and intermittent fevers. She was found to have thrombocytopenia to 15,000. Infectious workup was negative except for Rhinovirus/Enterovirus on viral panel. HIV and HHV8 were negative. MRI Abdomen showed hepatosplenomegaly and computed tomography [...]

Case Presentation: A 77-year-old African-American male with Adult-onset Still’s disease (AOSD) was admitted at the hospital for severe thrombocytopenia. The patient had been diagnosed with AOSD four years before this hospital admission. His AOSD was well-controlled with anakinra, an interleukin-1 receptor antagonist, and low-dose prednisone. On admission, the patient did not have any neurological manifestation. [...]

Case Presentation: 61-year-old woman history of type 2 diabetes mellitus presented to medicine clinic with complaint of rash on her face and legs. Exam revealed an erythematous rash over both ear lobes, arms, and extensor surface of both knees. There was no mucocutaneous involvement and no palpable purpura. Drug reaction was suspected, therefore tramadol and [...]

Case Presentation: 24-year-old female presented with greater than one month history of sporadic rash with migratory arthralgias, fevers, and pharyngitis with lymphadenopathy. Patient first developed a sporadic, erythematous, non-pruritic maculopapular rash that would wax and wane during a trip to Mexico two months prior to presentation. Patient also began to experience diffuse migratory arthralgias, starting [...]

Case Presentation: A 47-year-old man with a history of metastatic colon cancer status post resection and rheumatoid arthritis presented to the emergency department with 4 days of fever, shortness of breath, fatigue and myalgias. He described fevers in a periodic pattern with spikes occurring about 3 times per day. He was found to be tachycardic [...]

Case Presentation: A 29-year-old female with a past medical history of microcytic anemia and recently-diagnosed AOSD presented with 2 weeks of progressive dyspnea. On her preceding hospital admission, her AOSD was diagnosed and clinical suspicion for MAS was initially mounted. At that time, she demonstrated polyarthralgia, pruritic rash, high-grade fevers, hepatosplenomegaly, diffuse lymphadenopathy, neutrophilic leukocytosis, [...]

Case Presentation: 54-year-old male patient diabetes mellitus type II presented with pain and swelling involving small joints of bilateral hands with wrists. Synovitis involving bilateral interphalangeal, metacarpo-phalangeal were noted.Labs revealed leukocytosis to 15.7K/microL. Hemoglobin was 7.7 g/dL. Anemia work up revealed low serum iron level of 23 µg/dL, low TIBC at 167ug/dL with saturation of [...]

Case Presentation: A 19-year-old woman with a history of anxiety was admitted to the hospital with one week of fever to 103 degrees F, sore throat, fatigue, and severe arthralgias. History was notable for pleuritic chest pain, an intermittent rash over her arms and thighs, and a 23-pound weight loss over 12 months, which she [...]

Case Presentation: A 40-year-old female with adult-onset Still’s disease (AoSD) refractory to methylprednisolone and who had been recently started on anakinra 2 months prior to hospitalization was admitted with 2 weeks of fatigue, nausea, diffuse pruritis, jaundice, and intermittent fevers and rash. Exam was notable for jaundice and salmon-colored rashes on her trunk and back. [...]

Case Presentation: A 43-year-old man presented to the hospital with three days of lethargy, confusion, jaundice, abdominal pain with associated vomiting and poor oral intake. Medical history includes recently diagnosed Adult-onset Still’s Disease (AOSD) 6 weeks prior to presentation, for which he was taking prednisone 60 mg daily. Exam was notable for lethargy, petechiae on [...]