Case Presentation: A 29-year-old Caucasian woman presented to the emergency department with fever, sore throat, epigastric and right upper quadrant abdominal pain of 5 days duration. Physical examination was positive for fever (40oC), tachycardia (heart rate 114 beats per minute), and a palpable liver and spleen on abdominal examination. Notable laboratory investigations included pancytopenia – [...]

Case Presentation: A 27-year-old gentleman with no significant past medical history presented to our hospital with five days of persistent fevers with night sweats, sore throat, headache, vomiting, and neck pain. Upon initial evaluation, his temperature was 38.4° Celsius, heart rate of 130 beats/min, blood pressure of 126/78 mm of Hg, respiratory rate of 18 [...]

Case Presentation: A 31-year-old male with a past medical history significant for treated syphilis presented with a three-month history of recurrent fevers. Despite close outpatient follow-up and extensive workup, his symptoms persisted prompting him to go to the ED.On presentation, the patient was febrile, hypotensive, and tachycardic. He was admitted for sepsis and was started [...]

Case Presentation: A 26-year-old man with history of virally undetectable HIV, presented with 3 weeks of intermittent fevers and night sweats associated with chills, non-productive cough and generalized weakness, but denied weight loss. Vital signs revealed fever of 101.3F, tachycardia (pulse 118 bpm) and hypotension (blood pressure 95/61 mmHg). Physical exam revealed cervical and axillary [...]

Case Presentation: A 63-year-old male was admitted to the hospital for dizziness secondary to heart failure exacerbation and incidentally found to have thrombocytopenia of 141,000 on admission. Over the next 72 hours, the patient’s platelet count decreased by over 50% to 51,000 while all other cell lines remained stable. The patient had not received any [...]

Case Presentation: A 63-year-old male with hypertension and a history of thalassemia trait presented to the ED for evaluation of two weeks of progressive malaise and widespread tender lymphadenopathy. One week prior, the patient started a course of doxycycline for presumed tick-borne illness by his primary care provider, but worsening symptoms along with diarrhea, vomiting, [...]

Case Presentation: A 71 year old woman with a history of rheumatoid arthritis with multiple previous emergency room visits for fever presented with fatigue and weakness. Over the past few months she had nearly daily fevers, with decreased oral intake and urination over the past week. Her family members had previously tested positive for Influenza, [...]

Case Presentation: A 41-year-old female with Acquired Immunodeficiency Syndrome (AIDS) presented with a complex clinical picture involving seizures, falls, and fever. Limited historical information hindered a comprehensive understanding of the patient’s medical background. Upon examination, the patient exhibited signs of cachexia, lethargy, and distinctive skin lesions. Laboratory results revealed anemia, leukocytosis, and a significantly low [...]

Case Presentation: 81-year-old man initially presented to his primary care physician for a persistent cough of three weeks associated with new onset shortness of breath when climbing stairs. He had a normal chest X-Ray, but also a mild anemia. Initial work-up was targeted at evaluation for a gastrointestinal bleed. He underwent a CT abdomen/pelvis, upper [...]

Case Presentation: A 62-year-old man with type 2 diabetes was hospitalized with a two-week history of fatigue, sore throat, diarrhea, and 18-pound weight loss. In the ED, he was hypotensive and tachycardic, which improved with IV fluids. Physical exam was significant for bilateral posterior cervical lymphadenopathy and splenomegaly. Labs showed leukocytosis (25.8K) with 18.2% lymphocytic [...]