Case Presentation: An elderly male with a pertinent past medical history of carpal tunnel syndrome, and chronic diarrhea, presents with complaints of progressively worsening anasarca and associated dyspnea. He has had multiple hospitalizations for dyspnea over the last six months, thought to be due to transudative pleural effusions. Outpatient work-up, including echocardiogram and subspecialty consultation [...]

Case Presentation: A 74-year-old female with a history of restless leg syndrome, hypertension, GERD, presented with worsening fatigue, shortness of breath, and anasarca over the last 6 months. Labs revealed anemia (hemoglobin, 8.0 g/dL), thrombocytopenia (platelet count, 46K/μL), reticulocyte count 11.4%, undetectable serum haptoglobin, serum LDH >2700 U/L, ferritin 1223 ng/mL, negative direct Coomb’s test, [...]

Case Presentation: We describe a rare case of a nephrotic syndrome (NS) as a complication of secondary syphilis (SS), which resolved with appropriate treatment of the infection. This is a 54 year-old male with no pertinent medical history, who presented to clinic with bilateral palmar rash. He was diagnosed of secondary syphilis with positive Venereal [...]

Case Presentation: A 66-year-old female with a history of hypertension presented to the emergency department with one week of lower extremity edema, nausea, and vomiting. On admission, the patient was found to be hyponatremic, hypoalbuminemic, with nephrotic range proteinuria (urine protein-to-creatinine ratio of 8.5 g/g) and acute kidney injury. During the hospital course, the patient’s [...]

Case Presentation: A 63 year old African-American Male with a history of well-controlled hypertension and hyperlipidemia presented with a four day history of new-onset lower extremity, upper extremity, and abdominal swelling. He denied shortness of breath, chest pain, orthopnea, and constitutional symptoms, but did report occasional non-drenching night sweats. He reported being otherwise healthy with no known history of [...]

Case Presentation: A 19 year-old woman without significant past medical history was admitted to the medicine service with shortness of breath, nausea, and severe edema. Over the past 2-3 months, she had experienced worsening diffuse swelling and associated 30-lb weight gain. In the few days prior to admission, she had increased cough and difficulty breathing [...]

Case Presentation: A 29 year-old-woman was found to have proteinuria on routine labs that later progressed over the next few months to nephrotic syndrome with worsening lower extremity edema. Her work up revealed a positive (antinuclear antibody) ANA titer of 1:640. However, her anti-dsDNA and serum complement levels were normal, and she did not meet [...]

Case Presentation: A 50-year-old woman with prior cerebrovascular accident, paroxysmal atrial fibrillation, hypertension, and diabetes who presented for her second syncopal episode in as many months. Her exam was unremarkable aside from chronic neurologic deficits and new lower extremity swelling. Initial labs revealed elevated creatinine and large protein on her urinalysis with a very low [...]

Case Presentation: A 69-year-old Africa-America female presented with one month of worsening bilateral lower extremity swelling/edema. She was nonoliguric. She denied chest pain, orthopnea or dysuria. The patient was diagnosed with adult T-cell leukemia/lymphoma two months prior to admission. She was initially treated with interferon and lamivudine, which were stopped due to prolonged neutropenia. Then, [...]

Case Presentation: A 49-year-old male with a history of warfarin non-compliance left popliteal deep vein thrombosis (DVT), was admitted for dyspnea, left arm pain and bilateral lower extremities edema. In addition to new evidence of DVTs, the patient was found with nephrotic syndrome (NS). Chest CT showed concern for bronchogenic malignancyand enlarged kidneys. He underwent [...]