Case Presentation: A 54-year-old woman with type 2 diabetes mellitus with hyperglycemia and hypertension presented to our hospital with new fevers, nausea, vomiting.Four days prior, the patient was found to have a diabetic foot infection and started on trimethoprim/sulfamethoxazole (TMP-SMX) and metronidazole as an outpatient. At this time, her sodium was 133, corrected to 139 [...]

Case Presentation: A 61-year-old man presented to the emergency department with acute onset of fevers, myalgias and generalized erythematous rash after taking five weeks of Trimethoprim-sulfamethoxazole (TMP-SMX) for acute prostatitis. Vital signs were notable for fever and tachycardia, with relative hypotension which responded to initial fluid resuscitation. The patient initially denied abdominal pain however the [...]

Case Presentation: 75 y/o F with metastatic anal cancer to lungs status post right lung lobectomy on leucovorin, oxaplatin and fluorouracil every 2 weeks, HTN and SLE presents with a 3-day history of weakness, sore throat, and mouth sores. Pt was in the Dominican Republic for 10 days and upon return, endorsed fatigue and sore [...]

Case Presentation: A 41-year-old African American male with a past medical history of overactive bladder and benign prostatic hyperplasia presented to the emergency department (ED) with increasing proximal bilateral lower extremity muscle pain for five days. His pain was accompanied with increasing difficulty with ambulation. The patient also noted persisting hematuria, urgency, and hesitancy for [...]

Case Presentation: 73-year-old male had a witnessed fall at home with a minor head injury without loss of consciousness. Later, his wife noted him having new onset convulsive seizures and immediately notified EMS. Upon EMS arrival, he was alert but confused- his fingerstick glucose measured 11 mg/dL. He received oral glucose and was transferred to [...]

Case Presentation: A 70-year-old male with medical history significant for rheumatoid arthritis presented to the emergency department with several days of odynophagia, oral ulcers, skin lesions and epistaxis. He was treated for foot cellulitis with TMP-SMX for one week prior to admission. The patient had been receiving 10 mg SQ weekly injectable MTX for Rheumatoid [...]

Case Presentation: A 26-year-old otherwise healthy female was prescribed trimethoprim-sulfamethoxazole (TMP-SMX) for a recurring, spontaneously draining vaginal mass below her urethra with inguinal adenopathy. 5 days after starting TMP-SMX, she developed a full-body rash, fever, myalgia, nausea, and a depressed WBC of 2.4 K/mcL. Possible drug fever was suspected and TMP-SMX was discontinued and covered [...]

Case Presentation: A 31-year-old male with no significant past medical history presented with fever, chills, night sweats, and rash. One week prior, he underwent incision and drainage of a perirectal abscess and was started on a 7-day course of trimethoprim/sulfamethoxazole (TMP-SMX). On the second day following the procedure, he developed fevers, chills, night sweats, and [...]

Case Presentation: An 8-year-old boy presented with 8 days of lip swelling, crusting, peeling, and bleeding, causing poor oral intake and dehydration. Initial symptoms included cough, nasal congestion, and fever (100.4°F). He developed lip ulcerations and was seen multiple times with diagnosis of oral herpes and impetigo superinfection. After 4 days of adequate herpes/impetigo therapy, [...]

Case Presentation: A 26-year-old man with no significant past medical history presented to medical attention with severe oral mucositis. Approximately one week prior to his presentation, the patient developed symptoms of a respiratory illness with a productive cough, myalgias, and fever of up to 103 Fahrenheit. Although his respiratory symptoms began to improve, he developed [...]