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Meeting
Search Results for constipation
Abstract Number: 59
SHM Converge 2021
Background: Methylnaltrexone (MNTX) is a peripherally acting µ-opioid receptor antagonist indicated for opioid-induced constipation (OIC), which can be a serious consequence of opioid analgesia. We evaluated whether baseline osmotic agent (eg, milk of magnesia, polyethylene glycol, lactulose, sorbitol) or stimulant (eg, senna, bisacodyl) use affects the efficacy and safety of MNTX among a subgroup of […]
Abstract Number: 85
Hospital Medicine 2018; April 8-11; Orlando, Fla.
Background: Despite its prevalence, constipation is frequently under-recognized and treated with ineffective agents in hospitalized older adults. Methods: An anonymous survey was distributed to physicians regarding constipation management in hospitalized older adults. Chi-square or Fisher’s exact, as appropriate, were used to explore associations between demographics and survey answers. T-test was used to compare groups on […]
Abstract Number: G6
SHM Converge 2022
Background: Methylnaltrexone (MNTX) is a peripherally acting µ-opioid receptor antagonist indicated for opioid-induced constipation (OIC). We evaluated whether baseline use of laxatives, including stimulants, osmotic agents, stool softeners, or combinations thereof affects the efficacy and safety of MNTX. Methods: This post hoc analysis included pooled data from 2 multicenter, randomized, double-blind, placebo (PBO)-controlled, institutional review […]
Abstract Number: 180
SHM Converge 2023
Background: Almost three-quarters of hospitals with 50 or more beds have a palliative care program, and the percentage of annual hospital admissions receiving an initial palliative care consultation is more than 5%. Methylnaltrexone (MNTX) is a peripherally acting µ-opioid receptor antagonist indicated for opioid-induced constipation (OIC) in patients with advanced illness who are receiving palliative […]
Abstract Number: 185
Hospital Medicine 2018; April 8-11; Orlando, Fla.
Background: Constipation is a common pediatric complaint and cause of abdominal pain in the pediatric age group. Management for constipation is generally completed in the outpatient setting, but many patients may require inpatient management after failure of outpatient therapy. Methods: We utilized data from the 2012 Kids’ Inpatient Database (KID), a nationally representative sample of […]
Abstract Number: 402
Hospital Medicine 2018; April 8-11; Orlando, Fla.
Case Presentation: 21 month old male presents to the hospital for constipation that failed outpatient therapy. Parents describe one hard difficult to pass bowel movement (BM) every other day, without pencil thin stools, blood or mucus. Constipation began at 3 months of age when they introduced formula. He passed meconium within the 24 hours of […]
Abstract Number: 434
Hospital Medicine 2019, March 24-27, National Harbor, Md.
Background: Subcutaneous (SC) methylnaltrexone (MNTX) is approved for opioid-induced constipation (OIC) in adults with chronic noncancer pain and OIC in adults with advanced illness or with active cancer who require opioid dosage escalation for palliative care. This post hoc analysis evaluated data pooled from 3 randomized studies of patients with advanced illness and OIC. Methods: […]
Abstract Number: 472
SHM Converge 2021
Case Presentation: A 70-year-old male with a history of type 2 diabetes mellitus complicated by neurogenic bladder with indwelling catheter and severe peripheral vascular disease status post bilateral below knee amputations (BKAs) presented with watery diarrhea and nausea for 1 day. Both amputations were in the preceding four months. He required multiple rounds of antibiotics […]
Abstract Number: 477
SHM Converge 2021
Case Presentation: A 78-year-old man with heart failure, chronic kidney disease, and hereditary spastic paralysis was hospitalized with hyperkalemia to 7.7 mmol/L. He was admitted a month prior with heart failure and discharged on lisinopril with a new prescription for spironolactone. The patient had decreased appetite, limited oral intake, mild nausea, and no vomiting with […]
Abstract Number: 553
SHM Converge 2021
Case Presentation: We present a 55-year-old male with a history of chronic constipation refractory to extensive bowel regimens, disimpactions and colonoscopies. Patient presented to the Emergency Department with 5 months of constipation and a history of long periods of constipation since birth, sometimes lasting a year. On exam, patient’s abdomen was distended with decreased bowel […]