Background: Patients with diabetes who are hospitalized with COVID-19 have been found to have increased lengths of stay and greater intensive care unit utilization compared to those without diabetes. Diabetic ketoacidosis (DKA) is an acute diabetes emergency that accounts for a high number of hospitalizations, hospital readmissions, and healthcare utilization. Our study aims to evaluate [...]

Background: Diabetic Ketoacidosis (DKA) is the most common severe acute complication of diabetes, and has shown to be worsened by COVID-191. Several studies have found an association between COVID-19 and worsened outcomes from diabetic ketoacidosis (DKA).2 Vaccination against COVID-19 has led to substantial declines in the frequency, severity, and mortality from acute infection, but little [...]

Background: The presence of concomitant diabetic ketoacidosis (DKA) with acute pancreatitis (AP) is not uncommon and is associated with unfavorable outcomes (1,2). However, the diagnosis of AP in DKA patients is often missed because of the overlapping clinical features. Data comparing clinical characteristics and outcomes of patients with co-existing DKA and AP with DKA alone [...]

Background: Diabetic ketoacidosis (DKA) remains one of the commonest causes of medical and intensive care unit hospitalisations. DKA is a preventable hospital admission which is associated with multiple modifiable risk factors. However, little is known about factors that can predict healthcare resource utilisation in DKA. Previous studies have explored clinical and biochemical factors affecting the [...]

Background: Length of stay (LOS) is an important outcome measure in the evaluation of the quality of care for hospitalized patients. LOS in adults with diabetic ketoacidosis (DKA) is reported to be about 3 days, but detailed information about LOS in pediatric patients with DKA is lacking. Knowledge of factors that impact LOS is essential [...]

Background: COVID-19 has placed an unprecedented strain on healthcare systems worldwide, increasing demand for critical care beds1. To address shortage of critical care beds, innovative methods to increase capacity are needed. At our large, urban academic safety-net hospital, patients with diabetic ketoacidosis (DKA) are admitted to critical care units for intravenous (IV) insulin administration and [...]

Background: At our urban, academic hospital, use of outdated protocols and unnecessary variations in the care of DKA patients treated with ICU requiring IV insulin protocols have led to multiple safety events, delays in care with associated increased costs, and overtreatment of hyperglycemia with ketosis frequently resulting in unnecessary ICU utilization. After multi-disciplinary stakeholder development [...]

Background: Diabetic ketoacidosis (DKA) is a serious, acute complication of diabetes mellitus caused by a state of insulin deficiency requiring exogenous insulin administration.  Significant variation in intensive care unit (ICU) admission rates for DKA exists among hospitals, due to patient- and institution-specific factors, with rates ranging from 16-81%.  Patients with DKA admitted to an ICU [...]

Case Presentation: Mr. O is a 28 year old Navy cadet with no significant past medical history who presented to the Emergency Department with three days of malaise, nausea, polyuria, and polydipsia in the setting of recent steroids for a new rash. On presentation, Mr. O’s glucose returned at 624 mg/dL, pH was 7.28 and [...]

Case Presentation: We are presenting a case of a 71-year-old male patient with a history of hypertension, non-insulin dependent type 2 diabetes mellitus (DM) well controlled on metformin, and non-invasive high grade urothelial bladder cancer diagnosed in 2014 treated with transurethral resection of the prostate and intravesicular mitomycin. In 2016, his bladder cancer has progressed [...]