Background: Individuals with autoantibodies against melanoma differentiation-associated protein 5 (MDA-5) are reported to have a significant risk of developing rapidly progressive and fatal interstitial lung disease (ILD) in clinically amyopathic dermatomyositis patients (CADM). Previous cohort studies of dermatomyositis patients who have been systematically evaluated for the presence of anti-MDA5 antibodies and associated clinical features and [...]

Case Presentation: A 68-year-old man with hypertension and osteoarthritis presented with fever, cough, dyspnea, and weight loss for 2 months. Prior to admission, he had received antibiotics for community-acquired pneumonia without improvement. Physical exam showed multiple ulcers at the base and sides of tongue, bilateral palmar erythematous papules with ulceration and scaling, bilateral erythematous plaques [...]

Case Presentation: A 65-year-old female with a past medical history of hypertension, hyperlipidemia, coronary artery disease, and tobacco abuse was admitted to the hospital for worsening shortness of breath and cough. The patient was initially admitted to the hospital for cough and shortness of breath. CT chest revealed multifocal pneumonia and the patient was started [...]

Case Presentation: A 44 year-old male with a history of gout presented with bilateral hand swelling, muscle weakness, fatigue, rash, and shortness of breath. The symptoms have progressed for the last 6 months to the point of inability to walk more than a block and needing assistance getting up despite a course of standard gout [...]