Background: Japan has the high incidence of tuberculosis with the rapid population aging in developed county. In acute care hospital, delaying in respiratory isolation for tuberculosis can cause serious hospital-acquired infections and subsequent delay in the initiation of treatment, which might be poor prognosis for not only the patient but also the around medical providers. [...]

Background: TOUR™ is a multicenter study designed to characterize the real-world population characteristics and clinical outcomes associated with telavancin (TLV) use through retrospective medical chart review. Telavancin is a lipoglycopeptide antibacterial active against gram-positive pathogens, including methicillin-sensitive and -resistant Staphylococcus aureus (MSSA and MRSA). In the US, TLV is approved for hospital-acquired (HABP) and ventilator-associated [...]

Background: Respiratory rate (RR) is an independent predictor of in-patient mortality, intensive care unit admission and cardiac arrest across a variety of conditions. It is also an integral component of many risk prediction calculators (such as the pneumonia severity index). Thus, accurate assessment of RR is necessary to recognize disease severity and prognosis among hospitalized [...]

Background: Advancements in technology have expanded accessibility to telemetry via remote monitoring and resulted in increased application in hospitalized patients. The American Heart Association (AHA) telemetry guidelines restrict use to patients with sepsis, severe electrolyte disturbances or primary cardiac conditions. Respiratory infections have emerged as a common source of hospitalization and telemetry is frequently applied [...]

Background: The ratio of partial pressure of arterial oxygen to the fraction of inspired oxygen (P:F ratio) has known clinical utility. For example, it is a key component of the sequential organ failure assesment (SOFA) score which is a validated mortality predictor and the new operational defintion of sepsis. Yet, its use is limited because [...]

Background: The coronavirus disease 2019 (COVID-19) pandemic has dramatically altered how clinicians care for hospitalized patients in the setting of a highly contagious respiratory disease. Changes seen across hospitals include implementation of medical distancing guidelines (i.e. reduced in-person patient contact) and creation of respiratory isolation units (RIUs) for patients with COVID-19. While medical distancing has [...]

Background: Research suggests that COPD patients with low peak inspiratory flow rate (PIFR,

Background: The COVID-19 pandemic was one of the biggest threats to human health, affecting health and health care delivery systems at both the individual and institutional level. There have been varied reports about how sociodemographic factors affect outcomes of patient with COVID-19 [1] [2] [3]. In this US claims based study, we analysed discharge data [...]

Background: COPD exacerbations are among the leading causes of hospital readmissions. According to the COPD Foundation, in 2013, 22% patients admitted for COPD exacerbation required readmission within 30 days of discharge. This represents a significant burden in terms of morbidity for these patients and increased cost to the healthcare system. The COPD readmission rate during [...]

Background: Hospital readmission rates are heavily scrutinized, and are utilized as a measure of the quality of care provided by hospitals. In the Oklahoma City Veterans Affair Health Care System (VAHCS), there was a significant increase in the number of cardiorespiratory 30-day readmissions in the month of September (8% to 14%). Most patients (76%) were [...]