Case Presentation: A term 8-month-old infant was admitted to the hospital for concerns of inconsolable crying and diffuse hypertonicity in all four extremities. Birth history was unremarkable and newborn screens were negative. Her history was significant for loss of developmental milestones at 6-7 months of age, characterized by inability to sit without support or to [...]

Case Presentation: A previously healthy 10 year-old girl was admitted directly to the pediatric ward with several weeks of fever of unknown origin, lower extremity edema, right groin edema, erythema and pain. She frequently traveled to Mexico and lived in a farm-type setting.She had been treated for cellulitis with at least 7 different antibiotics at [...]

Case Presentation: A 17-year-old healthy male teenager presented with 2 weeks of bilateral lower extremity weakness with paresthesia, urinary retention, blindness of the left eye, left relative afferent pupillary defect, and retained deep tendon reflexes. An MRI of the orbit, brain, and spine showed left optic neuritis and transverse myelitis extending from T9 to the [...]

Case Presentation: An 8-year-old HIV-negative boy presented to a hospital in Malawi in septic shock secondary to typhoid fever with ileocecal perforation. He underwent repair and peritoneal washout without bowel resection. He was treated with ceftriaxone, metronidazole and supportive care. Initial labs were notable for hemoglobin of 10g/dl, platelets of 22/dL, and WBC 2.8/dL. Two [...]

Case Presentation: A 5-month-old male presented to the hospital for further workup of 15 days of fever. In the preceding 2 weeks, he had intermittent symptoms, including cough, rhinorrhea, and diarrhea. He was treated for an ear infection with antibiotics about 5 days into the course for suspected otitis media without resolution of his fever. [...]

Case Presentation: A 19-year-old male with no significant medical or psychiatric history presented for evaluation of altered mental status and agitation in the setting of cannabis ingestion. The patient reported consuming a cannabis edible followed by 24 bottles of water due to excessive thirst. He presented to the emergency department by ambulance and required chemical [...]

Case Presentation: A previously healthy 8 year old male presented to the emergency department (ED) with a one day history of diffuse abdominal pain, nausea, non-bloody and non-bilious vomiting, and fever up to 39˚C. Appendix ultrasound was normal. Urinalysis was significant for protein, ketones, and bilirubin. Influenza A/B PCR was negative. He improved with intravenous [...]

Case Presentation: 1 year old otherwise healthy twins present to the ED after Twin A became acutely unresponsive. The twins had been ill with a GI virus with fever, vomiting, and decreased activity for a week. The night of presentation, Twin A started vomiting, developed perioral cyanosis, and became unresponsive. On arrival to the ED, [...]

Case Presentation: Patient is a 15 yo boy with PANDAS, epilepsy, ADHD, and developmental delay presented with 9 days of decreased ambulation, abdominal pain, headache, and fatigue. Initially, his symptoms were attributed to recent fall and recent IVIG infusion. However, the patient then developed anorexia, weight loss, and aggressive behavior prompting admission. On exam, he [...]

Case Presentation: An otherwise healthy 9-year-old, fully vaccinated, male initially presented to urgent care with acute onset of sore throat, fever, trouble swallowing, and mild intermittent dyspnea. Due to worsening respiratory distress the patient was brought to an emergency department where he was found to have hoarse voice, trismus and in sniffing position. Laboratory testing [...]