Case Presentation: Hemophagocytic lymphohystiocytosis (HLH) is a rare cause of pancytopenia. Patients with sickle cell disease can present with pancytopenia and recognition of (HLH) in patients with sickle cell disease may be a lifesaving diagnosis.Case presentation:A 39-year-old female with past medical history of sickle cell anemia and moyamoya disease was admitted with sickle cell vaso-occlusive [...]

Case Presentation: A 27-year-old gentleman with no significant past medical history presented to our hospital with five days of persistent fevers with night sweats, sore throat, headache, vomiting, and neck pain. Upon initial evaluation, his temperature was 38.4° Celsius, heart rate of 130 beats/min, blood pressure of 126/78 mm of Hg, respiratory rate of 18 [...]

Case Presentation: A 61 year old male with a past medical history of hypertension, hyperlipidemia, and obstructive sleep apnea presented to the hospital with fever. He reported 1 week of fever to 103 F with associated rigors, abdominal pain, confusion, and decreased urine output. He reported a keen interest in outdoor activities such as hiking. [...]

Case Presentation: A 26-year-old man with history of virally undetectable HIV, presented with 3 weeks of intermittent fevers and night sweats associated with chills, non-productive cough and generalized weakness, but denied weight loss. Vital signs revealed fever of 101.3F, tachycardia (pulse 118 bpm) and hypotension (blood pressure 95/61 mmHg). Physical exam revealed cervical and axillary [...]

Case Presentation: A 23-year-old male with granulomatosis with polyangiitis with renal involvement (on azathioprine), stage 4 chronic kidney disease (baseline renal function) presented with fever, weight loss, and new pancytopenia. Broad-spectrum antibiotics were started and a comprehensive infectious work-up was done, including bacterial cultures, viral tests, and fungal serologies. Initial imaging was unremarkable for any [...]

Case Presentation: A 57-year-old man with congestive heart failure and coronary artery disease presented with shortness of breath of two days duration. He denied fevers, chills, chest pain, or cough. Presenting vitals were significant for oxygen saturation of 80%, requiring. All other vitals were within normal limits. Physical exam was unremarkable. His labs were significant [...]

Case Presentation: A 56-year-old male with a past medical history of hemophagocytic lymphohistiocytosis (HLH), in remission following chemotherapy in 2018, left MCA CVA in 2016 without significant residual deficits, restless leg syndrome, neurodegenerative motor neuron disease with lower extremity spasticity, and peripheral neuropathy was brought to the hospital for weeks of increasing confusion and generalized [...]

Case Presentation: A 27-year-old incarcerated female with no past medical history presented with abdominal pain and fevers. Initial workup demonstrated neutropenia, anemia, and thrombocytopenia as well as an elevated ferritin level of 2000mg/dL. Abdominal imaging revealed hepatomegaly and diffuse adenopathy concerning for a lymphoproliferative disorder. A comprehensive workup revealed a positive EBV PCR, positive HSV [...]

Case Presentation: A healthy 29 y/o male with mild COVID 19 illness three weeks prior presented to the emergency department with one week of fevers, chest pain and shortness of breath. Patient denied recent travel, sick contacts, and was not on any medications.On presentation he was febrile to 103oF and persistently hypotensive after fluid resuscitation. [...]

Case Presentation: A 27-year-old female without any significant medical history, who developed acute kidney injury, metabolic acidosis, increasing liver enzymes, coagulopathy, anemia, thrombocytopenia and undifferentiated shock requiring pressors on 6th post-partum delivery. Peripheral smear showed atypical lymphocytes, dohle bodies and neutrophils with toxic vacuolization, suggesting an inflammatory processOther labs were significant for elevated ferritin levels [...]