Background: Complex non-pharmacologic interventions containing multiple, or bundled, components can successfully prevent and treat hospital-acquired delirium in older adults. However consistent implementation, and the measurement of compliance, of these bundled interventions can be challenging to sustain in hospital settings especially in presence of COVID-19. Developing workflows with a smaller sub-set of components that are feasible […]

Background: Complex non-pharmacologic interventions containing multiple, or bundled, components can successfully prevent and treat hospital-acquired delirium in older adults. However consistent implementation, and the measurement of compliance, of these bundled interventions can be challenging to sustain in hospital settings especially in presence of COVID-19. Developing workflows with a smaller sub-set of components that are feasible […]

Background: Alcohol withdrawal is a common issue in hospitalized patients and is associated with significant morbidity and mortality. Alcohol withdrawal occurs when the gamma aminobutyric acid (GABA) stimulating effect of alcohol is removed, resulting in an excess of the excitatory neurotransmitter glutamate. Treatment typically consists of as needed benzodiazepines, which activate GABA. However, this reactive […]

Background: Panel-based Nucleic acid amplification tests (NAATs) are laboratory tools that are used to detect small quantities of RNA or DNA to rapidly identify a multitude of infectious organisms. A systematic review and meta-analysis looking at the diagnostic accuracy of the BioFire® FilmArray® meningitis-encephalitis (ME) panel which is used at our institution showed that it […]

Background: Proton pump inhibitors (PPIs) have been associated with adverse events and increased mortality in patients diagnosed with cirrhosis (1). PPIs are commonly prescribed to patients with cirrhosis who present to the hospital with gastrointestinal bleeds (2). However, guidelines do not suggest routine usage of PPI in patients with cirrhosis without gastroesophageal reflux disease (GERD) […]

Background: Patients spend about 95% of their hospitalization in bed, increasing the risk of functional decline associated with adverse events and readmissions. Some hospitals track patients’ functional mobility trends using Activity Measure for Post-Acute Care 6-Clicks Inpatient Short Form (AM-PAC). We aim to understand the associations between functional mobility loss from hospital admission to discharge, […]

Background: While NT-proBNP has been known to predict mortality in heart failure patients and in hospitalized patients, its association with mortality in healthy adults without a history of cardiovascular disease is unknown. Further, it is unclear if a one-time measurement of NT-proBNP can predict distant mortality. Therefore, we examined the association between NT-proBNP with all-cause […]

Background: Patient experience is an important outcome for hospitals. These outcomes impact insurer payments, hospital ratings, and perceived quality of care (1). Like many hospitals, our patient experience is measured using Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) surveys administered by Press Ganey (PG). Response rates to PG surveys are low, especially from […]

Background: The social determinants of health (SDOH) are widely recognized as having an important impact on health and mortality with up to 80% of health outcomes shaped by SDOH domains ( the conditions in which people are born, grow, work, live, and age). There is strong evidence that addressing unmet social needs can lower healthcare […]