Background: Among patients undergoing cardiac surgery on cardiopulmonary bypass (CPB), post-operative complications are common, occurring in up to 67% of patients, and significantly impact long-term outcomes. We conducted a Phase 2 clinical trial of RBT-1, a pharmacologic preconditioning drug, to assess cytoprotective biomarkers and clinical outcomes. Herein, we report our final results. Methods: This randomized, [...]

Background: Patients with End-stage renal disease (ESRD) who are dialysis-dependent have an elevated risk of peri-operative morbidity and mortality. There are many scoring tools that can help predict perioperative risk. Unfortunately, none were validated specifically for patients with ESRD. We aimed to compare the performance of the Revised cardiac risk (RCRI) and the AUB-HAS2 scores [...]

Background: Patients undergoing cardiac surgery are at risk of anemia from blood loss, inflammation, and red blood cell lysis, necessitating blood product utilization and increasing the risk of post-operative complications. RBT-1 (a combination of stannic protoporfin and iron sucrose) is a novel preconditioning drug administered prior to surgery that upregulates anti-inflammatory, antioxidant, and iron scavenging [...]

Background: The emergence of hospitalists over the last 25 years as leaders in quality, safety, and value-based care has resulted in improvements in hospital throughput and reduction of in-hospital complications (1). The keys to success are standardizing clinical pathways and interdisciplinary collaboration. At Tampa General Hospital (TGH), our hospitalist team observed significant variability in the [...]

Background: Background: As healthcare systems evolve to provide more efficient and patient-centered care, the utilization of ambulatory surgery centers (ASCs) has become increasingly common. These centers offer a convenient and cost-effective alternative to traditional inpatient hospitalization for a wide range of surgical procedures. However, proper preoperative evaluation and decision-making are critical to ensure patients are [...]

Case Presentation: 34 yo female nonsmoker with PCOS and hirsutism on spironolactone admitted for sleeve gastrectomy for obesity.   Pre-op bp 117/50. BP began to increase intraoperatively and postoperatively into the evening with a maximum bp of 181/104.  She experienced intractable post-op emesis. After the surgery, she noted chest pain, shaking and numbness in her hands which resolved by the morning. On [...]

Case Presentation: A 66-year old woman with a history of obesity and hypertension presented with a right femoral neck fracture after a mechanical fall. She underwent a right total hip arthroplasty and the anesthesiologist reported transient intraoperative hypoxia during cement placement. In the recovery room, the patient was hypotensive, tachycardic and hypoxic requiring up to [...]

Case Presentation: We are reporting the case of a 25-year-old Hispanic gentleman with a strong family history of Familial Adenomatous Polyposis (FAP) and Colorectal Cancer (CRC) who presented for evaluation of abdominal pain, recurrent bloody stools, and profound weight loss. Initial Hb was 7.2 g/dL, and abdominal examination showed generalized rigidity and tenderness worse in [...]