Background: Kidney dysfunction is a risk factor for several health problems, such as ischemic heart disease, stroke, peripheral artery disease, chronic kidney disease, and gout. This study aims to analyze the global disease burden caused by kidney dysfunction at the national, regional, and territorial levels. Methods: As part of our ecological investigation, we used the [...]

Background: The global impact of the COVID-19 pandemic has been profound, with significant disparities in infection and mortality rates, particularly in high-risk populations. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that complicates patient management in the context of COVID-19, given the increased risk of infections and limited guidance on pharmacological management. Methods: This [...]

Case Presentation: A 66-year old woman, with a history of renal transplant for diabetes related end-stage renal disease, was admitted to the hospital by her transplant team, for significantly abnormal serum creatinine level of 8.6 mg/dL from her baseline creatinine value of 1.6 mg/dL. Of note, she underwent cystoscopy by urology 2 weeks prior for [...]

Case Presentation: An 81-year-old man with a history of heart failure (HF) and recent diagnosis of an ileocecal mass with associated bulky lymphadenopathy and peritoneal carcinomatosis (Figure 1) presented to the emergency room with decreased appetite, abdominal pain, and worsening abdominal distention. Upon arrival, the patient was afebrile and hemodynamically stable. Physical examination was remarkable [...]

Case Presentation: A 41-year-old woman with a history of nephrolithiasis managed conservatively presented to the hospital with right flank and right upper quadrant pain. The pain initially started four months prior to her presentation, cramping in nature, rated 10/10 in intensity, intermittent, progressively worsening, initially well managed with ibuprofen, aggravated by movement, and relieved partially [...]

Case Presentation: A 71-year-old patient with a past medical history of hypertension, insulin-dependent type two diabetes mellitus with peripheral neuropathy, and deceased donor kidney transplant two years prior (CMV D-/R+ & EBV D+/R+) presented with a complaint of acute onset dark urine, and progressively worsening nausea, vomiting, and intermittent diarrhea. His immunosuppressive regimen consisted of [...]

Case Presentation: An 88-year-old woman comes to the emergency department with a four-day history of left-sided flank pain associated with nausea and emesis. She has a history of essential hypertension, dyslipidemia, anxiety, and diverticulitis, with a prior history of partial colectomy. For hypertension, she has been on triamterene-hydrochlorothiazide 75 mg-50 mg once daily for several [...]

Case Presentation: An 87-year-old woman with a history of pancreatic cancer status post distal pancreatectomy/splenectomy/partial colectomy, chronic kidney disease, hepatocellular carcinoma, and diabetes was admitted following sudden onset of new, uncontrollable bilateral upper extremity shaking and facial twitching. Symptoms started the night before and became progressively worse with dyspnea, nausea, and bilateral lower extremity tremors [...]

Case Presentation: A 50-year-old woman with prior cerebrovascular accident, paroxysmal atrial fibrillation, hypertension, and diabetes who presented for her second syncopal episode in as many months. Her exam was unremarkable aside from chronic neurologic deficits and new lower extremity swelling. Initial labs revealed elevated creatinine and large protein on her urinalysis with a very low [...]

Case Presentation: A 71 year old male presents to the ED with diffuse abdominal pain and nausea for the day. He has an extensive medical history including Type II DM, CAD, HFpEF, and COPD. He was recently prescribed Bactrim for a UTI, but notes persistent dysuria and suprapubic discomfort which prompted him to take an [...]