Background: Throughout the COVID-19 pandemic, clinicians have sought to identify risk factors for severe disease to help guide hospital algorithms, resource allocation and therapeutics. Older age, high Charlson Comorbidity Index (CCI), D-dimer and C-reactive protein (CRP) are associated with severe disease (1-5). CCI and SaO2/FiO2 ratio are associated with mortality, but the changing SaO2 in [...]

Background: The risk of thrombosis and bleeding in hospitalized patients with Coronavirus disease 2019 (COVID-19) is uncertain. Early studies suggested patients with COVID-19 may develop a unique coagulopathy marked by elevated thrombotic risk which has led some institutions to recommend stronger thromboprophylaxis in these patients. Our goal was to quantify the incidence of thrombosis and [...]

Background: The novel coronavirus disease 2019 (COVID-19) has demonstrated a range of presentations and outcomes affecting multiple organ systems. Acute kidney injury (AKI) associated with hospitalized patients with COVID-19 and related outcomes vary widely according to early reports. This study aimed to determine the prevalence of AKI, AKI in the setting of chronic kidney disease [...]

Background: Age has been implicated as the main risk factor for COVID-19-related mortality. Yet, critical factors relevant to older patients, such as baseline function and life-sustaining treatment preferences, have not been considered. The objective of this study was to determine patient factors associated with mortality in hospitalized older adults with COVID-19. Methods: A retrospective cohort [...]

Background: Coronavirus disease of 2019 (COVID-19) is a novel widespread disease that has a range of manifestation from asymptomatic to fatal. In the United States, there have been approximately 396,000 hospitalizations as of this writing, of which an estimated 25% will require the intensive care unit (ICU)1,2. With the ongoing spread and repeated waves of [...]

Background: The coronavirus disease 2019 (COVID-19) pandemic has dramatically altered how clinicians care for hospitalized patients in the setting of a highly contagious respiratory disease. Changes seen across hospitals include implementation of medical distancing guidelines (i.e. reduced in-person patient contact) and creation of respiratory isolation units (RIUs) for patients with COVID-19. While medical distancing has [...]

Background: In current times, physicians are working to older ages, lending experience and knowledge that benefits both patient care and education. Recent findings demonstrate advanced age as a risk factor for severe morbidity and mortality from serious acute respiratory syndrome-coronavirus-2 (COVID-19), placing older physicians at high-risk during the current pandemic. Pediatric hospitalists frequently care for [...]

Background: Sleep is critical to children’s health and recovery, but pediatric inpatient sleep is often disrupted by nonessential overnight interruptions. The COVID-19 pandemic necessitated social distancing policies which minimized contact with low-risk patients. These policies have the potential to decrease overnight disruptions and improve sleep for hospitalized patients. Methods: This cohort study compared sleep disruptions [...]

Background: COVID-19 has placed an unprecedented strain on healthcare systems worldwide, increasing demand for critical care beds1. To address shortage of critical care beds, innovative methods to increase capacity are needed. At our large, urban academic safety-net hospital, patients with diabetic ketoacidosis (DKA) are admitted to critical care units for intravenous (IV) insulin administration and [...]

Background: Proper hand hygiene is a cornerstone of infection control [1,2]. Despite this, compliance remains a challenge, averaging only 50% across healthcare systems nationwide [1].Several interventions have been trialed to improve compliance, including audit and feedback [3]. Traditionally, hand hygiene audits have occurred through direct observation. Unfortunately, this approach can capture fewer than 1-3% of [...]