Background: COVID-19 (Coronavirus Disease of 2019) is a global pandemic caused by the rapidly spreading SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). The novel coronavirus has stressed the limits of healthcare systems globally, making early identification of risk factors essential to the functioning of our healthcare systems during this ongoing pandemic. Many risk factors are already [...]

Background: There has been conflicting data regarding the effect of comorbid asthma on severity of illness with COVID-19 disease. The prevalence of asthma reported in hospitalized patients as compared to the local population has varied widely across studies and areas of the world. Furthermore, the risk for testing positive for SARS-CoV-2 as well as the [...]

Background: The SARS-CoV-2 (COVID-19) outbreak is rapidly spreading worldwide and as a result clinical predictors of disease severity are critical for appropriate management and disposition of patients. An early and accurate risk stratification of COVID-19 patients may have a great impact on their prognosis given rapid patient deterioration and continued need for rationing of treatments. [...]

Background: The COVID-19 RT-PCR test is a real-time reverse transcription polymerase chain reaction (rRT-PCR) test for the qualitative detection of nucleic acid from SARS-CoV-2 virus (8). False negative RT-PCR tests pose a serious challenge as they can lead to diagnosis and treatment delays as well as increased risk of viral transmission in the community (1-10). [...]

Case Presentation: A 40-year-old healthy woman, presented with two weeks of cough, nasal congestion, sore throat, intermittent fevers, fatigue, and myalgia but no weakness. She tested positive for the SARS-Cov-2. Physical exam showed no neurologic deficit. Two weeks later, respiratory symptoms were improving but she developed sudden, leg pain, numbness, and weakness. She described it [...]

Case Presentation: This is a unique case of acquired thrombotic thrombocytic purpura (aTTP) due to the novel SARS-CoV-2 virus (COVID-19). Our patient is a 36-year old male with hypertension, alpha-thalassemia trait, who presented with abdominal pain. He has a family history pertinent for a sister with immune thrombocytopenic purpura. He was found to have cholecystitis [...]

Case Presentation: A 36-year-old male with a renal transplant (CMV serostatus: donor positive/recipient negative) presented to an outside hospital with fever and acute hypoxic respiratory failure requiring high flow oxygen. His maintenance immunosuppressants included cyclosporine and mycophenolate. Upon admission, he was started on treatment for community acquired pneumonia and severe COVID-19 pneumonia. Due to lack [...]

Case Presentation: We present a 12-year-old female with paresthesia and swelling to the left lower extremity. She was seen in the outpatient setting two weeks prior and diagnosed with cellulitis. After only two days of antibiotics, she presented to the Emergency Department for worsening symptoms; she was noted to have a blue, cold, and swollen [...]

Case Presentation: A twenty-year-old female with acute lymphoblastic leukemia presented to the ED with one day of fever and a non-productive cough. Her vitals were significant for a fever of 102.8 F. Lung auscultation revealed diminished air entry to the right lower lung field. The rest of her physical exam was unremarkable.Chest radiograph demonstrated a [...]

Case Presentation: A 15-year-old female with history of migraines presented to the emergency department with six days of headache, fatigue, and fever to 105F. Three days prior, she developed diffuse body aches and severe neck pain. On the day of presentation, the patient developed a nonpruritic rash on her face, trunk, and extremities. She had [...]