Case Presentation: A 30-year-old woman with triple positive (Beta-2-glycoprotein IgG/IgM, anticardiolipin IgG/IgM, and lupus anticoagulant) antiphospholipid syndrome (APS) taking apixaban, aspirin, and hydroxychloroquine presented to the emergency department for progressive confusion, emesis, and hematochezia found to be in cardiogenic shock due to right ventricular failure with critical limb ischemia due to complete right popliteal artery [...]

Case Presentation: A 55 year-old woman with past history of antiphospholipid syndrome complicated by multiple deep vein thromboses and miscarriages, prior hemorrhagic stroke, chronic slow GI bleed with iron deficiency anemia, thrombocytopenia, and CKD stage 3 presents to the ED with two-month history of progressively worsening shortness of breath and chest discomfort with exertion, which [...]

Case Presentation: A 48-year-old male with a past medical history of deep vein thrombosis (DVT) and pulmonary embolism (PE) presented with one day of severe chest pain, dizziness, and brief loss of consciousness resulting in a head injury. EKG showed T wave inversions in inferior leads and elevated troponin to 625 within a few hours. [...]

Case Presentation: A 65-year-old woman with antiphospholipid syndrome (APLS), and history of multiple lower extremity deep vein thrombosis (DVT) and miscarriages, on warfarin presented with syncope, fall, and head-strike. She was found to have an acute subdural hematoma (SDH) in the interhemispheric fissure and a non-occlusive DVT in the left femoral vein. Initial labs showed [...]

Case Presentation: A 63-year-old gentleman with a history of unprovoked left lower leg deep vein thrombosis (DVT) on rivaroxaban and seizure disorder on phenytoin, presented with acute onset abdominal pain, hematochezia, vomiting for two days. On presentation patient was tachycardic with a heart rate of 130/min, a physical exam revealed a distended and tender abdomen. [...]

Background: The American Society of Hematology (ASH) advises against routine thrombophilia testing in hospitalized patients with new venous thromboembolism (VTE) due to the potential for inaccurate results during the acute phase of the disease. Thrombophilia testing is generally reserved for outpatient follow-up, once the acute event has resolved. However, testing may be appropriate in specific [...]

Case Presentation: A 24-year-old male with a six-year history of systemic lupus erythematosus (SLE) presented to the emergency department with acute, severe left-sided abdominal pain accompanied by nausea and vomiting. His medical history included lupus nephritis, but his disease had been poorly managed due to noncompliance and inadequate follow-up. He denied previous similar episodes.On physical [...]

Case Presentation: A 25 year old male with no past medical history was admitted for progressively worsening burning chest pain and shortness of breath associated with diaphoresis, nausea, vomiting, and left arm numbness. Initial electrocardiogram showed STEMI in the inferior and antero-lateral leads, and a troponin of 2.15. Emergent cardiac catheterization revealed a mid left [...]

Case Presentation: A 61-year-old male with a history of alcohol abuse and Insulin-dependent diabetes mellitus presented with complaints of retrosternal chest pain and multiple bouts of coffee-ground emesis for three days. He reported a three-day binge of drinking vodka prior to the presentation. On examination, he was tachycardic, tachypneic, but normotensive. Hand and tongue tremors [...]