Case Presentation: The patient is a 27-year-old male with lupus anticoagulant with hypoprothrombinemia syndrome (LAHPS)/triple positive antiphospholipid syndrome (APLS) in the setting of systemic lupus erythematous (SLE) and immune thrombocytopenia (ITP) on hydroxychloroquine, mycophenolate mofetil (MMF), and prednisone for immunosuppression, who presented to the ER with worsening right upper quadrant and epigastric pain. RUQ US [...]

Case Presentation: A 20-year-old female, nonsmoker, G1P0 at 25 weeks, presented to the ED with left leg swelling. Ultrasound confirmed a left femoral DVT. CBC and CMP were unremarkable. She started enoxaparin 80mg twice daily and followed with OB/GYN. Her hypercoagulable workup showed a prolonged aPTT and DRVVT, which corrected with mixing, indicating absence of [...]

Case Presentation: A 56-year-old Caucasian female with history of mechanical aortic and mitral valves on chronic warfarin therapy, atrial fibrillation, and questionable history of SLE was admitted to the intensive care unit for emergent splenectomy following a motor vehicle accident. After initially being sent home from a regional hospital, she was diagnosed five days later [...]

Case Presentation: Our patient is a 39 year old G2 P0111 female with PMH of Type 1 diabetes mellitus and Hashimoto’s thyroiditis, s/p NSVD at 34 weeks due to previous pre-eclampsia (occurring 1 month prior to admission), who complained of acute dyspnea on exertion, orthopnea, lower extremity edema, and a 1-month history of fatigue and [...]

Case Presentation: A 65 year-old man with primary antiphospholipid syndrome (APS) was transferred to our hospital for management of refractory thrombocytopenia and thrombosis. His disease was diagnosed by positive lupus anticoagulant, anti-cardiolipin antibody, beta-2-glycoprotein IgM and IgG, and was well controlled with warfarin for years. His worsening APS was precipitated by traumatic subdural hematomas and [...]

Case Presentation: Twenty three year old female presented with complaints of severe headache and dizziness since past 2 weeks. Her past medical history was significant for SLE, heart failure with reduced ejection fraction and lupus pericarditis. CT head showed possible left cerebellar stroke of indeterminate age and hence was admitted for the stroke workup. Few [...]

Case Presentation: A 37 year old female with a past medical history of Hypertension, Ischemic Cardiomyopathy (EF=40-45%), Systemic Lupus Erythematosus, and Antiphospholipid Antibody Syndrome presented to the Emergency Department with complaints of pleuritic chest pain that had been persistent for two days duration which radiated down her left arm. Initial laboratory workup noted a normal [...]

Case Presentation: A 30-year-old woman with triple positive (Beta-2-glycoprotein IgG/IgM, anticardiolipin IgG/IgM, and lupus anticoagulant) antiphospholipid syndrome (APS) taking apixaban, aspirin, and hydroxychloroquine presented to the emergency department for progressive confusion, emesis, and hematochezia found to be in cardiogenic shock due to right ventricular failure with critical limb ischemia due to complete right popliteal artery [...]

Case Presentation: A 55 year-old woman with past history of antiphospholipid syndrome complicated by multiple deep vein thromboses and miscarriages, prior hemorrhagic stroke, chronic slow GI bleed with iron deficiency anemia, thrombocytopenia, and CKD stage 3 presents to the ED with two-month history of progressively worsening shortness of breath and chest discomfort with exertion, which [...]

Case Presentation: A 48-year-old male with a past medical history of deep vein thrombosis (DVT) and pulmonary embolism (PE) presented with one day of severe chest pain, dizziness, and brief loss of consciousness resulting in a head injury. EKG showed T wave inversions in inferior leads and elevated troponin to 625 within a few hours. [...]