Case Presentation: We present a case of a 21-year-old previously healthy male with a history of marijuana use who was admitted to the hospital with neuropsychiatric symptoms, including confusion, agitation, disorganized behavior, and significant unintentional weight loss. The patient had recently moved to the United States from Guatemala. Initial examination revealed that he was disoriented [...]

Case Presentation: A 73-year-old male with a history of recurrent follicular lymphoma (on lenalidomide), atrial fibrillation, coronary artery disease, and heart failure presented with dyspnea, weight gain, and bilateral leg swelling. On admission, diffuse erythematous rash with superficial peeling and erythroderma was noted, without mucosal involvement. Skin biopsy revealed psoriasiform lichenoid dermatitis with eosinophils, apoptosis, [...]

Case Presentation: An 83 year old male with past history significant for chronic obstructive pulmonary disease, active tobacco use disorder, essential hypertension, hyperlipidemia, complete heart block (status post permanent pacemaker), polycythemia, and thrombocytopenia (prior SPEP had shown two faint IgG lambda restrictions of unclear significance) presented to the emergency department with chest pain after a [...]

Case Presentation: A 62 year-old patient with stage III chronic kidney disease (baseline serum creatinine ~2.0 mg/dL), chronic obstructive pulmonary disease, and heart failure with preserved ejection fraction (HFpEF) was admitted from dermatology clinic with a painful body-wide rash. Two years prior to admission, he had a rash on the legs that improved with topical [...]

Case Presentation: A 59-year-old man with a history of long-term tobacco use, alcohol use disorder, hypertension, and left total knee arthroplasty (TKA) 30 years prior presented with a recurrent left knee infection. He initially developed MRSA septic arthritis in October 2023 and underwent prosthesis removal with antibiotic spacer placement, followed by a course of daptomycin, [...]

Case Presentation: The patient is a 22-year-old female with known history of Crigler-Najjar Syndrome Type 2, diagnosed in infancy. Both parents are recessive carriers of the UGT1A1 gene missense mutation. Her symptoms are typically well-maintained at home with intermittent phototherapy and nightly phenobarbital. The patient reports her baseline bilirubin levels are typically ~8 mg/dL. The [...]

Case Presentation: A 65-year-old female with uterine carcinosarcoma was hospitalized for ascites, dyspnea, and fatigue. Initial findings revealed peritoneal carcinomatosis with massive ascites, potential liver metastases, and acute kidney injury (AKI) with creatinine 6.6 mg/dL (baseline 0.9) with oliguria. She declined dialysis. High urate (14.5 mg/dL) prompted administration of rasburicase due to an initial concern [...]

Case Presentation: A 70-year-old man with hypothyroidism and a prior clinical diagnosis of temporal arteritis (untreated with high-dose steroids) presented with several months of progressive cognitive and behavioral changes, recurrent sinusitis refractory to multiple antibiotic courses, and ~20 lbs unintentional weight loss. Over the prior 2–3 months, he developed persistent bilateral hand and foot paresthesias [...]

Case Presentation: A 36-year-old female with no prior medical history presented with progressive dyspnea, orthopnea, and bilateral lower extremity edema. On admission, she was severely hypertensive (BP 203/138 mmHg) and tachycardic (HR 103 bpm). Laboratory studies revealed hemoglobin 6.9 g/dL, serum creatinine 10.8 mg/dL (prior baseline 0.9 mg/dL), BUN 112 mg/dL, and urine protein-to-creatinine ratio [...]

Case Presentation: A 71-year-old male with recent history of gallstone pancreatitis and no known liver disease or malignancy presented with epigastric pain, nausea, and vomiting. Laboratory evaluation revealed lipase of 66 U/L, mild transaminitis, and negative viral hepatitis and HIV serologies. Contrast-enhanced CT showed interval improvement of pancreatitis, with a new occlusive thrombus throughout the [...]