Background: Gastrointestinal (GI) malignancies are a leading cause of cancer mortality accounting for ~28% of cancer deaths in the U.S. [1]. Perforation, peritonitis, and septic shock are severe complications often presenting later in the disease course and associated with surgery, prolonged hospitalization, and mortality [2]. Social determinants of health (SDOH) including race, socioeconomic status, and [...]

Background: Patients living with pain associated conditions often experience a remitting and relapsing course resulting in frequent emergency department (ED) visits and hospitalizations. The optimal approach to management varies between patients and patient- centered therapy should be specific to each patient. However, healthcare fragmentation, distrust, clinician assumptions, and differences in clinician practices all contribute to [...]

Background: Acute pancreatitis (AP) is a common cause of hospitalization in the United States. The aim of our study is to investigate the impact of gender on the outcomes of AP in adult patients hospitalized with AP. Methods: We performed a retrospective study of adult patients with AP utilizing the 2020 Nationwide Inpatient Sample (NIS) [...]

Background: Patient-directed discharge – defined as leaving the hospital prior to completing recommended medical treatment – is associated with increased morbidity and mortality and occurs in 10-20% of hospitalizations for patients with opioid use disorder (OUD). Patients with OUD often cite untreated pain and withdrawal as contributing to their decision to leave the hospital by [...]

Background: Hepatorenal syndrome-acute kidney injury (HRS-AKI), characterized by rapid deterioration in renal function, is a serious complication of decompensated cirrhosis and is associated with significant morbidity and mortality. While terlipressin is the only FDA-approved treatment in the U.S. for adults with HRS-AKI, real-world evidence on its use and outcomes remains limited. We conducted a retrospective [...]

Background: As bedside procedure services become more prevalent and their impact on patient satisfaction and length of stay become evident, the volume of procedures expected of services rises. These procedures require assistance from a bedside nurse for consent, patient positioning, medication administration, and lab acquisition. This pulls nurses away from their duties to other patients [...]

Background: Acute pancreatitis is a common gastrointestinal condition associated with significant morbidity and healthcare utilization. Hospital at Home (HaH) programs have emerged as an alternative to traditional brick-and-mortar (B&M) hospitalization, offering hospital-level care in the home setting. While HaH has demonstrated feasibility for various conditions, clinical characteristics and outcomes for pancreatitis patients managed by HaH [...]

Background: Vitamin K is frequently administered in cirrhosis to correct elevated INR, yet its efficacy and clinical benefit remain uncertain. We systematically reviewed and synthesized its effect on INR, responder rates, and bleeding outcomes. Methods: PubMed/PMC were searched through September 2025. Eligible studies included cirrhotic patients receiving vitamin K with reported INR or bleeding outcomes. [...]

Background: In 2025, CMS implemented a new inpatient quality measure to report on age-friendly care, the 4Ms Framework: what matters, medications, mentation, and mobility. Hospitalization at Home (HaH) provides hospital-level care to patients in the comfort of their own homes. This study assesses whether HaH delivers age-friendly care aligned with the 4Ms Framework. Methods: We [...]

Background: Patients with liver disease have complex hemostatic abnormalities that can cause severe hematologic complications. Although they are known to be at increased risk for bleeding, newer evidence has dispelled the notion that they are protected from venous thromboembolism (VTE). Liver disease is also associated with multiple complications, such as varices, ascites, and hepatic encephalopathy, [...]